In Vivo study of patented collagen biomaterial shows promise for pelvic floor reconstruction

Through collaborative translational research at University Hospitals Cleveland Medical Center and Case Western Reserve University, a team of physicians and engineers has developed a novel woven collagen mesh material for potential use in mid-urethral sling (MUS) surgeries.

Over the past decade, exploration of effective biomaterials for treatment of stress urinary incontinence (SUI) and pelvic floor reconstruction has gained attention in response to concerns about synthetic mesh complications.

“The quest for synthetic mesh alternatives aims to address an unmet need for an ideal implantable material,” says Adonis Hijaz, MD, Director, Female Pelvic Surgery at UH Cleveland Medical Center and Vice Chair of Academics and Research for the UH Urology Institute. “Our overarching mission is to help our patient population and give women a safe, durable repair for incontinence or prolapse.”

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